I want to use an assembler to assemble the unmapped illumina reads from an alignment to S288C (yeast genome). So far I have been using SSAKE and it seems to be working fine, but I would like to compare the results of SSAKE to another assembler. Are there better/other assemblers out there that would be worth trying? Thanks for your time, sorry if this is a repost.
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The complexity of cancer is clearly demonstrated in the diverse ecosystem of the tumor microenvironment (TME). The TME is made up of numerous cell types and its development begins with the changes that happen during oncogenesis. “Genomic mutations, copy number changes, epigenetic alterations, and alternative gene expression occur to varying degrees within the affected tumor cells,” explained Andrea O’Hara, Ph.D., Strategic Technical Specialist at Azenta. “As...-
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