I want to use an assembler to assemble the unmapped illumina reads from an alignment to S288C (yeast genome). So far I have been using SSAKE and it seems to be working fine, but I would like to compare the results of SSAKE to another assembler. Are there better/other assemblers out there that would be worth trying? Thanks for your time, sorry if this is a repost.
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
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