Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • puggie
    Member
    • Nov 2011
    • 52

    #1

    Ideas for graphing data?

    I have developed a method that identifies some genomic features and does so tissue-specifically. Now I would like to make some visual representation of this. E.g in one type of tissue I get lets say 1000 hits of varying intensity across the genome chromosomes. In other tissues I could get lets say 500-1500 hits of varying intensity across chromosomes.

    It can be boiled down to a genomic coordinate accompanied by a intensity/frequency score. The coordinate is not super-important for the graphical representation, hence no need to depict the exact chromosome, however it would aid interpretation I guess.

    Is there some 'fancy' way of doing this besides a heatmap or the like for every chromosome?

    All inputs appreciated.
  • blancha
    Senior Member
    • May 2013
    • 367

    #2
    Circos plots?

    Comment

    • DPCook
      Member
      • Sep 2014
      • 10

      #3
      Originally posted by blancha View Post
      Circos plots?
      I second this. Circos plot with histogram tracks for each tissue could look really good. The only problem I can see would be resolution. If you want to show differences within small ranges (eg. Differences in histone marks within a 100kb range), this may not be best. Because the plot represents the whole genome, a single pixel often represents ~1Mb. However if you can bin your values into ~1Mb windows, you're golden.

      aesthetics,alignment,analysis,bioinformatics,cancer,circos,circular,comparative,conservation,data visualization,design,evolution,evolutionary,gene,genetic,genome,genome sciences centre,genomic,genomics,graph,graphics,human,human genome,infovis,martin krzywinski,rearrangement,science,sequence,somatic,structural,synteny

      Comment

      • Richard Finney
        Senior Member
        • Feb 2009
        • 701

        #4
        Some guy named Ying Hu wrote some Circos thing in R (Who?)

        OmicCircos is an R software package used to generate high-quality circular plots for visualizing genomic variations, including mutation patterns, copy number variations (CNVs), expression patterns, and methylation patterns. Such variations can be ...


        OmicCircos: A Simple-to-Use R Package for the Circular Visualization of Multidimensional Omics Data

        Comment

        Latest Articles

        Collapse

        • SEQadmin2
          Beyond CRISPR/Cas9: Understand, Choose, and Use the Right Genome Editing Tool
          by SEQadmin2



          CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).

          Despite this, “CRISPR helped turn genome editing from a specialized technique into
          ...
          07-31-2026, 11:01 AM
        • SEQadmin2
          Proteomic Platforms: How to Choose the Right Analytical Strategy to Improve Detection and Clinical Applications
          by SEQadmin2


          Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.

          The systematic characterization of the human proteome has
          ...
          07-20-2026, 11:48 AM

        ad_right_rmr

        Collapse

        News

        Collapse

        Topics Statistics Last Post
        Started by SEQadmin2, Today, 10:35 AM
        0 responses
        7 views
        0 reactions
        Last Post SEQadmin2  
        Started by SEQadmin2, 08-06-2026, 07:41 AM
        0 responses
        24 views
        0 reactions
        Last Post SEQadmin2  
        Started by SEQadmin2, 08-03-2026, 10:13 AM
        0 responses
        41 views
        0 reactions
        Last Post SEQadmin2  
        Started by SEQadmin2, 07-31-2026, 02:55 AM
        0 responses
        47 views
        0 reactions
        Last Post SEQadmin2  
        Working...