Hi, i have chip-seq data from an isogenic cell model where i am looking to determine which peaks overlap between various data-sets and also what the changes in fold enrichment are between them. I have considered using bedtools intersect to determine overlaping peaks but how can i determine the difference in fold enrichment, many peaks share location but differ in enrichment. This is for TF chip.
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NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification,...10-30-2026, 06:46 AM
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