Unconfigured Ad

Collapse
X
Collapse
 
  • Page of 1
  • Filter
  • Time
  • Show
Clear All
new posts
Previous template Next
  • Yasmin Lima
    Junior Member
    • Jan 2016
    • 2
    #1

    dbNFSP annotation

    Hello everyone

    I am a beginner in the next generation world.

    I have some data to analyze and I am confused about the dbNFSP database annotation...

    I can interpret very well the annotation because I can find easy information about the range scores of some algorithms, like PhyloP, LTR, MutationTaster and other. Do they range from 0 to 1, 0 to 10, or what?

    I mean, I have a value but I can interpret because I don't know which are the parameters...

    I have used Annovar, but the Annovar documentation for these algorithms is very poor in informations about.

    Anyone knows where I can find these informations, please?
    Tags: None
  • vivek_
    PhD Student
    • Jul 2012
    • 164
    #2
    You can get the descriptions from a readme file included in the dbNSFP distribution.

    Jpopgen - dbNSFP
    https://sites.google.com/site/jpopgen/dbNSFP
    Please access the current dbNSFP at dbNSFP.org. LEGACY VERSIONS (1.x - 4.x) INTRODUCTION: dbNSFP is a database developed for functional prediction and annotation of all potential non-synonymous single-nucleotide variants (nsSNVs) in the human genome. Its current version is based on the Gencode

    Comment

    Previous template Next

    Latest Articles

    Collapse
    • SEQadmin2
      Nine Things a Sample Prep Scientist Thinks About Before Sequencing
      by SEQadmin2


      I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.

      Here are nine questions we think about, in roughly the order they matter, before...
      06-18-2026, 07:11 AM
    • SEQadmin2
      From Collection to Sequencing: Why Sample Preparation and Preservation Define Sequencing Data
      by SEQadmin2


      Data variability is still an issue in sequencing technologies despite the advances in reproducibility and accuracy of these platforms. But the problem does not originate in the sequencing itself, but in the previous steps, before the sample reaches the sequencer.

      The first step is collection, followed by preservation and sample preparation for analysis. Most scientists overlook those steps, but not being careful might just be skewing the experiment’s results.
      ...
      06-02-2026, 10:05 AM
    View All

    ad_right_rmr

    Collapse

    News

    Collapse
    Topics Statistics Last Post
    Whole-Genome Sequencing Traces Faroe Islands Ancestry to a North Atlantic Founder Population by SEQadmin2
    Started by SEQadmin2, 06-17-2026, 06:09 AM
    0 responses
    30 views
    0 reactions
    		 Last Post SEQadmin2
    by SEQadmin2
    06-17-2026, 06:09 AM  
    Sequencing the Two-Toed Sloth Genome Reveals Jumping Genes Tied to Its Extreme Metabolism by SEQadmin2
    Started by SEQadmin2, 06-09-2026, 11:58 AM
    0 responses
    96 views
    0 reactions
    		 Last Post SEQadmin2
    by SEQadmin2
    06-09-2026, 11:58 AM  
    A New Method Makes Hantavirus Genome Analysis Faster and More Accessible by SEQadmin2
    Started by SEQadmin2, 06-05-2026, 10:09 AM
    0 responses
    115 views
    0 reactions
    		 Last Post SEQadmin2
    by SEQadmin2
    06-05-2026, 10:09 AM  
    A New Single-Cell Method Maps DNA-Protein Interactions by SEQadmin2
    Started by SEQadmin2, 06-04-2026, 08:59 AM
    0 responses
    109 views
    0 reactions
    		 Last Post SEQadmin2
    by SEQadmin2
    06-04-2026, 08:59 AM  
    View All
    Working...