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  • __sequence
    Member
    • Jun 2011
    • 13
    #1

    Algebraic operations with genomic occupancy data

    Hi all,

    What is a proper software to calculate the average between several genomic coverage signals (e.g. several ChIP-seq replicates, with single base-pair resolution)?

    Thanks!
    Last edited by __sequence; 11-24-2017, 07:37 PM.
    Tags: chip-seq, coverage, occupancy
    • malcook
      Member
      • Sep 2009
      • 24
      #2
      wiggletools - you will probably want your bigwigs to be normalized, possibly as made easy with deepTools
      Last edited by malcook; 11-25-2017, 12:06 AM.

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        • __sequence
          Member
          • Jun 2011
          • 13
          #3
          Originally posted by malcook View Post
          wiggletools - you will probably want your bigwigs to be normalized, possibly as made easy with deepTools
          Thank you! Is there also a software that allows to perform such operations with BedGraph files?

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