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  • Dragen

    When I first heard about Dragen, it sounded interesting but recently Edico has started to make this platform available on AWS, as well as several Bioinformatics-as-a-service platforms, including DNANexus, Seven Bridges and Illumina's BaseSpace:
    http://edicogenome.com/dragen-in-the-cloud/

    I think we should all be taking a hard look at this for a couple of reasons:
    • These platforms bring it to a wide audience and make it user-friendly
    • Platform effects: It's a hardware platform with inherent limits on configurability. This will tend to drive users to stadardize on it and effectively freeze pipelines to this standard.
    • It's not available on all platforms.
    • It's really fast!


    Based on this, I think it's something to discuss because it's going to have a big impact on the industry.

  • #2
    You forgot the main arguments against DRAGEN

    -licenses are limited by throughput
    -licenses are REALLY expensive
    -licenses are limited by application (buy DNA-seq, can't do RNA-seq).

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