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New software: G-Morse : Annotating genomes with massive-scale RNA-sequencing

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  • New software: G-Morse : Annotating genomes with massive-scale RNA-sequencing

    Hi all,

    I would like to introduce G-Mo.R-Se (Gene Modelling using RNA-Seq), an approach aimed at building gene models directly from RNA-Seq.
    More detailed information here.

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    Genome Biol. 2008 Dec 16;9(12):R175.
    Annotating genomes with massive-scale RNA-sequencing.
    Denoeud F, Aury JM, Da Silva C, Noel B, Rogier O, Delledone M, Morgante M, Valle G, Wincker P, Scarpelli C, Jaillon O, Artiguenave F.

    ABSTRACT: Next generation technologies enable massive-scale cDNA sequencing (so-called RNA-Seq). Mainly because of the difficulty to align short reads on exon/exon junctions, no attempts have been made so far to use RNA-Seq for building gene models de novo, i.e. in the absence of a set of known genes and/or splicing events. We present G-Mo.R-Se (Gene Modelling using RNA-Seq), an approach aimed at building gene models directly from RNA-Seq and demonstrate its utility on the grapevine genome.

    PMID: 19087247 [PubMed - as supplied by publisher]

  • #2
    Nice work!

    olivier

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    • #3
      Is there a downloadable tool available for this?

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      • #4
        http://www.genoscope.cns.fr/externe/gmorse/

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        • #5
          Thanks a lot. Chipper. Have you tested it? I will definitely give it a try.

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