G1K have had pilot data up on their website for a few years now, but it appears that they still haven't published any genomes beyond the pilots. When I look at browser.1000genomes.org and display resequencing data, it shows sequence for the two pilot trios (6 genomes) and nothing more. Is that all there is?
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No, its not dead. Having heard about it at seminars and workshops, I think the answer is simply that may be all the data published so far. -
Not dead yet. But I presume hapmap is dead now???Comment
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1000 genomes really isn't dead look at both http://www.1000genomes.org and browser.1000genomes.org to see that
Hapmap has stopped producing new data and is no longer state of the art but the info is all still available from their websiteComment
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM
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