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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,198 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by dingkai0564, 08-31-2011, 09:27 PM
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6 responses
4,012 views
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by pari_89
05-26-2013, 01:12 PM
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Started by xinxinding, 05-25-2013, 03:00 PM
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0 responses
1,662 views
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by xinxinding
05-25-2013, 03:00 PM
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Started by Fad2012, 05-23-2013, 02:51 AM
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2 responses
1,247 views
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by Fad2012
05-25-2013, 04:02 AM
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Started by kdarbs, 05-24-2013, 06:17 PM
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1,101 views
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by kdarbs
05-24-2013, 06:17 PM
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Started by fahmida, 05-21-2013, 05:14 PM
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10 responses
3,396 views
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by Wallysb01
05-24-2013, 03:24 PM
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Started by nncy1105, 05-24-2013, 11:46 AM
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4 responses
2,383 views
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by nncy1105
05-24-2013, 01:44 PM
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Started by getzabeth, 05-22-2013, 04:22 PM
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3 responses
3,155 views
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by getzabeth
05-24-2013, 11:08 AM
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Started by vishalthapar, 05-24-2013, 04:47 AM
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2 responses
1,697 views
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by chadn737
05-24-2013, 07:34 AM
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Started by NGS_New_User, 05-24-2013, 06:33 AM
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1 response
1,529 views
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by JackieBadger
05-24-2013, 06:43 AM
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Started by kasthuri, 05-23-2013, 03:03 PM
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5 responses
3,479 views
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by kasthuri
05-24-2013, 06:00 AM
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Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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Yesterday, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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Today, 10:04 AM
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Yesterday, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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07-07-2026, 11:05 AM
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