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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,343 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,126 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by liu_xt005, 05-07-2013, 11:24 AM
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0 responses
2,054 views
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by liu_xt005
05-07-2013, 11:24 AM
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Started by BhariD, 05-07-2013, 10:50 AM
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0 responses
5,039 views
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by BhariD
05-07-2013, 10:50 AM
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Started by mhadidi2002, 05-07-2013, 03:56 AM
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1 response
3,274 views
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by rhinoceros
05-07-2013, 10:32 AM
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Started by mruizm, 05-07-2013, 07:11 AM
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3 responses
1,716 views
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by mruizm
05-07-2013, 10:31 AM
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Started by Dakduif, 05-07-2013, 05:42 AM
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0 responses
1,853 views
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by Dakduif
05-07-2013, 05:42 AM
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Started by chrishah, 08-30-2012, 08:10 AM
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7 responses
13,776 views
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by rob123king
05-07-2013, 04:48 AM
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Started by emartinez, 05-06-2013, 02:34 AM
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2 responses
2,696 views
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by Palecomic
05-06-2013, 11:44 PM
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Started by biznatch, 01-10-2011, 10:39 AM
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5 responses
9,648 views
0 reactions
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by simonandrews
05-06-2013, 11:38 PM
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Started by piemmea, 05-06-2013, 02:20 PM
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1 response
2,270 views
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by shi
05-06-2013, 02:26 PM
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Started by Hilary April Smith, 01-18-2013, 12:05 PM
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3 responses
4,582 views
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Last Post
by Simon Anders
05-06-2013, 11:07 AM
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by SEQadmin2
Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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by SEQadmin2
I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.
Here are nine questions we think about, in roughly the order they matter, before...-
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Started by SEQadmin2, Yesterday, 10:08 AM
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Yesterday, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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07-07-2026, 11:05 AM
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Started by SEQadmin2, 07-02-2026, 11:08 AM
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07-02-2026, 11:08 AM
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