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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,318 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by bio_boris, 02-06-2018, 01:02 PM
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by bio_boris
02-06-2018, 01:02 PM
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Started by Arouth, 02-12-2014, 11:46 AM
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3 responses
3,864 views
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by Fad2012
02-06-2018, 12:05 PM
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Started by mmlin, 02-05-2018, 11:11 PM
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2,431 views
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by mmlin
02-05-2018, 11:11 PM
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Started by ecSeq Bioinformatics, 12-20-2017, 05:38 AM
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2 responses
4,862 views
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Started by k-gun12, 02-01-2018, 07:54 AM
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4 responses
10,261 views
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by gringer
02-03-2018, 12:57 PM
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Started by nextgen2010, 02-02-2018, 12:12 PM
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0 responses
1,431 views
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by nextgen2010
02-02-2018, 12:12 PM
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Started by Panova, 02-01-2018, 09:09 AM
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1 response
4,318 views
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by jkbonfield
02-02-2018, 08:58 AM
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Started by SaraYones, 02-02-2018, 01:20 AM
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1,281 views
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by SaraYones
02-02-2018, 01:20 AM
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Started by gacarson, 02-01-2018, 11:44 AM
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2 responses
2,569 views
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by seb567
02-01-2018, 12:36 PM
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Started by lre1234, 04-17-2013, 11:05 AM
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6 responses
4,149 views
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by gacarson
02-01-2018, 12:35 PM
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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07-08-2026, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, Yesterday, 10:04 AM
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by SEQadmin2
Yesterday, 10:04 AM
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Started by SEQadmin2, 07-08-2026, 10:08 AM
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by SEQadmin2
07-08-2026, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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by SEQadmin2
07-07-2026, 11:05 AM
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