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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,629 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,249 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by ahli1981, 01-30-2012, 07:49 AM
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1 response
1,576 views
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by dpryan
01-30-2012, 08:44 AM
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Started by tractorsazi, 01-30-2012, 05:34 AM
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3 responses
3,131 views
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by arvid
01-30-2012, 07:50 AM
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Started by florian, 01-30-2012, 03:21 AM
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0 responses
4,250 views
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by florian
01-30-2012, 03:21 AM
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Started by vanbug, 01-27-2012, 03:35 AM
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5 responses
4,616 views
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by vanbug
01-30-2012, 03:13 AM
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About SOAP2
by hus
Started by hus, 01-26-2012, 06:51 PM
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3 responses
4,134 views
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by hus
01-30-2012, 12:20 AM
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Started by Darwin, 06-08-2010, 06:18 PM
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8 responses
12,059 views
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by arvid
01-30-2012, 12:11 AM
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Started by A_Morozov, 01-29-2012, 05:13 PM
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0 responses
1,610 views
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by A_Morozov
01-29-2012, 05:13 PM
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Started by SF_mallish, 01-29-2012, 12:25 PM
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1 response
2,503 views
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Started by SeqVicious, 01-27-2012, 02:12 PM
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6 responses
5,923 views
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by Jim Robinson
01-29-2012, 10:12 AM
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Started by roshanbernard, 12-15-2011, 05:28 PM
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5 responses
3,994 views
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Last Post
by SES
01-29-2012, 09:14 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Yesterday, 02:55 AM
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9 views
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by SEQadmin2
Yesterday, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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by SEQadmin2
07-23-2026, 11:41 AM
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