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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,159 views
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by ECO
12-25-2009, 06:45 PM
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Started by jawalsh2, 01-27-2012, 10:02 AM
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by jawalsh2
01-27-2012, 10:02 AM
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Started by Artur Jaroszewicz, 01-26-2012, 06:31 PM
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1 response
6,542 views
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by darked89
01-27-2012, 05:45 AM
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Started by Lizex, 01-26-2012, 11:21 PM
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by Lizex
01-26-2012, 11:21 PM
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Started by hlwright, 09-01-2011, 01:14 AM
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7 responses
12,381 views
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by lifeng.tian
01-26-2012, 10:40 PM
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Started by jay2008, 01-26-2012, 07:23 PM
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1,827 views
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by jay2008
01-26-2012, 07:23 PM
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Started by LauraR, 01-26-2012, 02:54 PM
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1 response
1,846 views
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by chencheni
01-26-2012, 04:01 PM
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Started by Kumar10, 01-26-2012, 02:31 AM
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1 response
1,394 views
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by Dario1984
01-26-2012, 04:00 PM
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Started by bogdan, 01-25-2012, 08:27 AM
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2 responses
2,196 views
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by bogdan
01-26-2012, 03:22 PM
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Started by sdl11, 01-26-2012, 02:55 PM
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2,160 views
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by sdl11
01-26-2012, 02:55 PM
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Started by jomaco, 01-26-2012, 12:12 PM
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1,627 views
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by jomaco
01-26-2012, 12:12 PM
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Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
Probing...-
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Today, 10:04 AM
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Yesterday, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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07-07-2026, 11:05 AM
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