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Closed, Sticky:
New Resources for 1000 Genomes
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35 responses
107,731 views
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by laura
12-05-2013, 02:37 AM
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Closed, Sticky:
Software packages for next gen sequence analysis
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236 responses
685,751 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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24 responses
5,484 views
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by ondovb
11-22-2011, 01:28 PM
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1 response
3,410 views
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by nilshomer
11-22-2011, 12:10 PM
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3 responses
2,307 views
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by nilshomer
11-22-2011, 12:08 PM
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1 response
3,131 views
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by biznatch
11-22-2011, 08:09 AM
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0 responses
2,463 views
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by MikeT
11-22-2011, 04:28 AM
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2 responses
3,864 views
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by grimmer
11-21-2011, 07:21 PM
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0 responses
1,709 views
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11-21-2011, 03:20 PM
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1 response
2,154 views
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11-21-2011, 02:33 PM
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5 responses
2,127 views
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by hohllp
11-21-2011, 01:40 PM
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2 responses
2,698 views
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11-21-2011, 01:34 PM
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No topics found.
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Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...07-31-2026, 07:00 AM
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM -
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...07-20-2026, 11:48 AM -
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
...07-09-2026, 11:10 AM