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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,674 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,658 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by dlm, 01-29-2009, 06:39 AM
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11 responses
4,108 views
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by xuer
04-13-2009, 05:27 AM
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Started by AnamikaDarwin, 04-10-2009, 06:27 AM
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1 response
4,641 views
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by lh3
04-10-2009, 11:47 PM
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Started by bioinfosm, 04-01-2009, 08:54 AM
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1 response
2,708 views
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by bioinfosm
04-10-2009, 08:39 AM
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Started by bioinfosm, 03-24-2009, 10:30 AM
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2 responses
2,535 views
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by bioinfosm
04-10-2009, 08:37 AM
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Started by anyone1985, 04-10-2009, 05:58 AM
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1 response
4,503 views
0 reactions
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by cariaso
04-10-2009, 08:27 AM
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Started by Pepe, 04-08-2009, 06:12 PM
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6 responses
3,635 views
0 reactions
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by jkbonfield
04-10-2009, 03:07 AM
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Started by foolishbrat, 04-08-2009, 01:07 AM
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2 responses
3,901 views
0 reactions
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by acnoll
04-09-2009, 07:01 AM
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Started by f85978, 04-04-2009, 10:49 PM
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4 responses
3,205 views
0 reactions
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by BioWizard
04-08-2009, 01:46 PM
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Started by AnamikaDarwin, 02-21-2009, 12:43 PM
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11 responses
4,666 views
0 reactions
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by kvarala
04-07-2009, 10:09 PM
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Started by hbbio, 04-07-2009, 09:33 AM
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3 responses
2,859 views
0 reactions
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Last Post
by apfejes
04-07-2009, 11:14 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, 08-06-2026, 07:41 AM
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0 responses
13 views
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by SEQadmin2
08-06-2026, 07:41 AM
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Started by SEQadmin2, 08-03-2026, 10:13 AM
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0 responses
30 views
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by SEQadmin2
08-03-2026, 10:13 AM
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Started by SEQadmin2, 07-31-2026, 02:55 AM
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0 responses
40 views
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by SEQadmin2
07-31-2026, 02:55 AM
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