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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,488 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,773 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by tirosho, 11-03-2016, 12:26 PM
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1 response
1,236 views
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by dcameron
11-03-2016, 03:24 PM
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Started by chrisLi, 11-03-2016, 12:52 PM
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0 responses
1,399 views
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by chrisLi
11-03-2016, 12:52 PM
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Started by SamCurt, 11-03-2016, 10:23 AM
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0 responses
1,200 views
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by SamCurt
11-03-2016, 10:23 AM
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Started by dsenalik, 11-03-2016, 06:01 AM
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2 responses
10,986 views
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by SNPsaurus
11-03-2016, 09:05 AM
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Started by yangjr, 08-14-2013, 07:36 AM
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3 responses
4,472 views
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by marika
11-03-2016, 08:20 AM
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Started by itop90, 11-03-2016, 07:34 AM
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0 responses
1,174 views
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by itop90
11-03-2016, 07:34 AM
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Started by LacquerHead, 10-28-2016, 12:04 PM
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3 responses
2,048 views
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by Dario1984
11-02-2016, 03:00 PM
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Started by hmortens, 07-09-2013, 11:29 AM
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6 responses
4,660 views
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by natasha321
11-02-2016, 02:54 PM
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Started by kintany, 10-18-2016, 08:12 AM
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2 responses
2,265 views
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by kintany
11-02-2016, 08:01 AM
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Started by dayhan, 10-27-2016, 10:23 AM
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8 responses
7,760 views
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Last Post
by dayhan
11-02-2016, 05:50 AM
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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by SEQadmin2
Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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07-08-2026, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, 07-13-2026, 10:26 AM
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22 views
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by SEQadmin2
07-13-2026, 10:26 AM
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Started by SEQadmin2, 07-09-2026, 10:04 AM
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0 responses
32 views
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by SEQadmin2
07-09-2026, 10:04 AM
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Started by SEQadmin2, 07-08-2026, 10:08 AM
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20 views
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by SEQadmin2
07-08-2026, 10:08 AM
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