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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,683 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
685,017 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by osilander, 11-02-2016, 01:08 PM
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3 responses
3,198 views
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by JVGen
11-04-2016, 09:39 AM
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Started by polsum, 11-21-2011, 11:20 AM
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8 responses
14,434 views
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by katka
11-04-2016, 08:07 AM
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Started by seru, 03-06-2012, 03:04 AM
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2 responses
2,961 views
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by dpryan
11-04-2016, 05:54 AM
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Started by sohnic, 06-09-2011, 05:54 AM
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2 responses
5,191 views
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by ahalfpen
11-03-2016, 05:28 PM
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Started by tirosho, 11-03-2016, 12:26 PM
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1 response
1,236 views
0 reactions
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by dcameron
11-03-2016, 03:24 PM
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Started by chrisLi, 11-03-2016, 12:52 PM
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0 responses
1,399 views
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by chrisLi
11-03-2016, 12:52 PM
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Started by SamCurt, 11-03-2016, 10:23 AM
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0 responses
1,200 views
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by SamCurt
11-03-2016, 10:23 AM
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Started by dsenalik, 11-03-2016, 06:01 AM
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2 responses
10,988 views
0 reactions
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by SNPsaurus
11-03-2016, 09:05 AM
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Started by yangjr, 08-14-2013, 07:36 AM
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3 responses
4,503 views
0 reactions
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by marika
11-03-2016, 08:20 AM
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Started by itop90, 11-03-2016, 07:34 AM
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0 responses
1,175 views
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by itop90
11-03-2016, 07:34 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
Channel: Articles
07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, Yesterday, 12:22 PM
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0 responses
12 views
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by SEQadmin2
Yesterday, 12:22 PM
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Started by SEQadmin2, 08-11-2026, 10:35 AM
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0 responses
14 views
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by SEQadmin2
08-11-2026, 10:35 AM
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Started by SEQadmin2, 08-06-2026, 07:41 AM
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0 responses
31 views
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by SEQadmin2
08-06-2026, 07:41 AM
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