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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,701 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
685,194 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by Strandlife, 08-29-2016, 04:57 AM
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1 response
3,714 views
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by Strandlife
09-22-2016, 10:08 PM
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Started by xn3x, 09-22-2016, 06:54 AM
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1 response
1,731 views
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Started by Balat, 08-30-2011, 06:58 PM
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11 responses
18,094 views
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by tahia
09-22-2016, 07:55 AM
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Started by newfie, 09-21-2016, 09:15 AM
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5 responses
6,184 views
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by GenoMax
09-22-2016, 06:17 AM
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Started by HelloRyan, 09-22-2016, 02:33 AM
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0 responses
1,382 views
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by HelloRyan
09-22-2016, 02:33 AM
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Started by antifolate, 09-21-2016, 09:08 PM
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0 responses
3,916 views
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by antifolate
09-21-2016, 09:08 PM
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Started by mht, 12-26-2013, 09:00 PM
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2 responses
3,054 views
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by ADELALU
09-21-2016, 08:29 PM
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Started by hxlei, 09-21-2016, 07:11 AM
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0 responses
3,373 views
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by hxlei
09-21-2016, 07:11 AM
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Started by aquleaf, 07-28-2011, 01:21 PM
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3 responses
2,955 views
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by ohmiyajohn
09-21-2016, 05:36 AM
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Started by lre1234, 09-20-2016, 06:46 PM
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2 responses
1,965 views
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by lre1234
09-21-2016, 04:26 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
Channel: Articles
07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, 08-13-2026, 12:22 PM
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0 responses
28 views
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by SEQadmin2
08-13-2026, 12:22 PM
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Started by SEQadmin2, 08-11-2026, 10:35 AM
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0 responses
22 views
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by SEQadmin2
08-11-2026, 10:35 AM
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Started by SEQadmin2, 08-06-2026, 07:41 AM
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0 responses
37 views
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by SEQadmin2
08-06-2026, 07:41 AM
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