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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,724 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
685,643 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by Hel, 03-09-2016, 06:23 AM
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3 responses
1,606 views
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by GenoMax
03-09-2016, 07:30 AM
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Started by lizzi, 04-07-2014, 02:46 PM
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9 responses
6,892 views
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by Kulvait
03-09-2016, 06:40 AM
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Started by bvk, 03-09-2016, 05:53 AM
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2 responses
2,199 views
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by bvk
03-09-2016, 06:12 AM
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Started by sandesh, 01-31-2015, 07:37 PM
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2 responses
3,496 views
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by Macspider
03-09-2016, 05:41 AM
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Started by dbob, 03-08-2016, 05:34 AM
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1 response
1,475 views
0 reactions
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by SylvainL
03-09-2016, 05:26 AM
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Started by liuhui, 03-08-2016, 05:54 PM
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0 responses
3,071 views
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by liuhui
03-08-2016, 05:54 PM
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Started by juanc, 03-08-2016, 04:08 PM
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0 responses
1,352 views
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by juanc
03-08-2016, 04:08 PM
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Started by jgreenbaum, 03-08-2016, 02:27 PM
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0 responses
5,083 views
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by jgreenbaum
03-08-2016, 02:27 PM
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Started by sjackman, 10-15-2012, 09:20 AM
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6 responses
11,078 views
0 reactions
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by dpryan
03-08-2016, 12:44 PM
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Started by AdrianP, 10-15-2013, 12:20 PM
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19 responses
12,558 views
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
Channel: Articles
07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, Yesterday, 10:32 AM
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9 views
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by SEQadmin2
Yesterday, 10:32 AM
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Started by SEQadmin2, 08-20-2026, 11:17 AM
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28 views
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by SEQadmin2
08-20-2026, 11:17 AM
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Started by SEQadmin2, 08-18-2026, 10:05 AM
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0 responses
32 views
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by SEQadmin2
08-18-2026, 10:05 AM
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