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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,716 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
685,536 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by Paulo Caldas, 01-24-2016, 07:23 AM
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2,506 views
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by Paulo Caldas
01-24-2016, 07:23 AM
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Started by eloise1234, 01-24-2016, 05:46 AM
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1,082 views
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by eloise1234
01-24-2016, 05:46 AM
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Started by Dmitry_Vel, 01-23-2016, 03:52 PM
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1,313 views
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by Dmitry_Vel
01-23-2016, 03:52 PM
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Started by mido1951, 01-22-2016, 03:13 PM
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10 responses
2,408 views
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Started by kostask, 01-22-2016, 06:06 AM
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3 responses
3,129 views
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Started by jazz710, 01-22-2016, 07:58 AM
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0 responses
2,580 views
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by jazz710
01-22-2016, 07:58 AM
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Started by krapulaxdoctor, 01-21-2016, 02:56 AM
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6 responses
6,428 views
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by HESmith
01-22-2016, 05:41 AM
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Started by ecSeq Bioinformatics, 11-25-2015, 03:07 AM
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2 responses
3,755 views
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Started by milo0615, 01-21-2016, 04:20 PM
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1,411 views
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by milo0615
01-21-2016, 04:20 PM
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Started by TPH, 01-21-2016, 12:34 PM
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1,476 views
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by TPH
01-21-2016, 12:34 PM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
Channel: Articles
07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, 08-20-2026, 11:17 AM
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17 views
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by SEQadmin2
08-20-2026, 11:17 AM
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Started by SEQadmin2, 08-18-2026, 10:05 AM
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25 views
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by SEQadmin2
08-18-2026, 10:05 AM
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Started by SEQadmin2, 08-13-2026, 12:22 PM
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42 views
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by SEQadmin2
08-13-2026, 12:22 PM
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