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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,631 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,278 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by tinguzman, 09-12-2015, 01:40 AM
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1 response
4,384 views
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by dpryan
09-12-2015, 03:19 AM
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Started by SylvainL, 09-09-2015, 02:13 AM
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6 responses
1,813 views
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by SylvainL
09-12-2015, 01:59 AM
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Started by johnsequence, 09-11-2015, 03:27 PM
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0 responses
2,045 views
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by johnsequence
09-11-2015, 03:27 PM
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Started by clsppb, 10-07-2012, 01:56 PM
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14 responses
11,097 views
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by akropor2
09-11-2015, 02:40 PM
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Started by aprice67, 09-11-2015, 12:00 PM
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0 responses
2,393 views
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by aprice67
09-11-2015, 12:00 PM
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Started by danova, 09-10-2015, 07:13 AM
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5 responses
4,304 views
0 reactions
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by danova
09-11-2015, 11:41 AM
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Started by aprice67, 09-08-2015, 09:09 AM
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1 response
2,525 views
0 reactions
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by aprice67
09-11-2015, 09:30 AM
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Started by abisko00, 09-11-2015, 08:17 AM
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0 responses
1,117 views
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by abisko00
09-11-2015, 08:17 AM
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Started by BM7, 09-10-2015, 04:14 AM
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1 response
2,649 views
0 reactions
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by cmccabe
09-11-2015, 05:46 AM
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Started by kostask, 09-09-2015, 08:15 AM
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2 responses
2,906 views
0 reactions
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Last Post
by kostask
09-11-2015, 02:55 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, 07-31-2026, 02:55 AM
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0 responses
14 views
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by SEQadmin2
07-31-2026, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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0 responses
15 views
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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0 responses
13 views
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by SEQadmin2
07-23-2026, 11:41 AM
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