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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,631 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,311 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by frymor, 08-14-2015, 12:29 AM
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7 responses
4,587 views
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Started by JT Guan, 04-16-2013, 09:32 PM
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2 responses
2,160 views
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by milo0615
08-18-2015, 01:28 PM
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Started by biocomputer, 08-14-2015, 09:51 AM
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3 responses
2,080 views
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by biocomputer
08-18-2015, 10:09 AM
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Started by ea11, 08-18-2015, 06:10 AM
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0 responses
1,198 views
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by ea11
08-18-2015, 06:10 AM
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Started by Rutia, 08-18-2015, 12:55 AM
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0 responses
2,172 views
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by Rutia
08-18-2015, 12:55 AM
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Started by Mchicken, 07-15-2015, 06:02 AM
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6 responses
2,735 views
0 reactions
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by kenietz
08-17-2015, 07:04 PM
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Started by Acacianpunk, 08-17-2015, 11:59 AM
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0 responses
993 views
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by Acacianpunk
08-17-2015, 11:59 AM
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Started by Portah, 01-31-2014, 02:45 PM
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1 response
2,541 views
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by Portah
08-17-2015, 10:04 AM
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Started by cz0013, 08-17-2015, 07:07 AM
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8 responses
8,848 views
0 reactions
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by cz0013
08-17-2015, 09:31 AM
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Started by sgrego08, 08-17-2015, 09:08 AM
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0 responses
961 views
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by sgrego08
08-17-2015, 09:08 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, 07-31-2026, 02:55 AM
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0 responses
17 views
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by SEQadmin2
07-31-2026, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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0 responses
15 views
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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0 responses
14 views
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by SEQadmin2
07-23-2026, 11:41 AM
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