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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,344 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,129 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by undergradmolly, 02-06-2020, 06:41 AM
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0 responses
2,120 views
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Started by JasperGeh, 02-04-2020, 06:56 AM
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2 responses
3,787 views
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by JasperGeh
02-06-2020, 12:36 AM
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Started by Mike2188, 02-03-2020, 10:18 AM
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2 responses
1,660 views
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by Mike2188
02-04-2020, 08:00 AM
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Started by emlas, 02-03-2020, 05:25 AM
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4 responses
1,469 views
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by GenoMax
02-03-2020, 05:23 PM
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Started by Mike2188, 02-03-2020, 08:21 AM
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0 responses
14 views
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by Mike2188
02-03-2020, 08:21 AM
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Started by emlas, 02-03-2020, 05:31 AM
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1 response
1,125 views
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by GenoMax
02-03-2020, 06:18 AM
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Started by Phoenix, 01-29-2020, 05:55 AM
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2 responses
2,527 views
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by Phoenix
01-31-2020, 11:01 PM
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Started by Hedi86, 01-30-2020, 06:47 AM
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4 responses
1,589 views
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by Hedi86
01-31-2020, 05:26 AM
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Started by brachysclereid, 05-03-2011, 09:10 AM
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2 responses
7,942 views
0 reactions
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by emmaharry
01-30-2020, 09:46 PM
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Started by myourshaw, 01-30-2020, 09:29 AM
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0 responses
1,311 views
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Last Post
by myourshaw
01-30-2020, 09:29 AM
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by SEQadmin2
Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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by SEQadmin2
I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.
Here are nine questions we think about, in roughly the order they matter, before...-
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Started by SEQadmin2, Yesterday, 10:08 AM
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Yesterday, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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07-07-2026, 11:05 AM
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Started by SEQadmin2, 07-02-2026, 11:08 AM
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07-02-2026, 11:08 AM
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