Originally posted by Ganesh Ujwal
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It's wrong. -
I opened Lehninger (Principles of biochemistry, 4th ed.) on page 293. I quote:
C is deaminated to U in a rate of 10^-7 in 24 hours, which means 100 mutations a day for a mammalian cell which would have lead to a A-U genome in a short time. One of the biggest turning points of evolution is thymine instead of uracil in DNA. You can dig it up and read more.The slow Cytosine deamination reaction seems innocuous enough, but is almost certainly the reason why DNA contains thymine rather uracilComment
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