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  • Ganesh Ujwal
    Member
    • Dec 2014
    • 16

    #1

    Why is uracil used in RNA rather than thymine?

    What is the advantage gained by the substitution of thymine with uracil? I have read previously that it is due to thymine being "better protected" and therefore more suited to the storage role of DNA, which seems fine in theory, but why does the addition of a simple methyl group make the base more well protected?
  • dpryan
    Devon Ryan
    • Jul 2011
    • 3478

    #2
    You should really be asking questions like this in a general biology group, such as the biology stack exchange.

    Comment

    • Ganesh Ujwal
      Member
      • Dec 2014
      • 16

      #3
      if you know the answer please answer my question?
      my questions are clear.

      Comment

      • GenoMax
        Senior Member
        • Feb 2008
        • 7142

        #4
        You could have taken a moment to do a search and get the answer for the question you asked: http://biology.stackexchange.com/que...r-than-thymine
        Last edited by GenoMax; 12-08-2014, 06:42 PM.

        Comment

        • Ganesh Ujwal
          Member
          • Dec 2014
          • 16

          #5
          so i never get answer from this site for this question?

          Comment

          • Brian Bushnell
            Super Moderator
            • Jan 2014
            • 2709

            #6
            From the FAQ:

            While the site is intended to be oriented toward life sciences and next generation sequencing, any scientific topic related to genomics is open for discussion.

            There's nothing wrong with your question. However, GenoMax did point you to an answer. Questions related to sequencing and processing tend to get answered here faster than theoretical biology questions, though.

            Comment

            • Ganesh Ujwal
              Member
              • Dec 2014
              • 16

              #7
              so, where should i post this question in seqanswers.com to get answers ?

              Comment

              • Brian Bushnell
                Super Moderator
                • Jan 2014
                • 2709

                #8
                Here or General are the best places. Like I said, there's nothing wrong with the question, but bioinformatics threads tend to generate more responses.

                Comment

                • Ganesh Ujwal
                  Member
                  • Dec 2014
                  • 16

                  #9
                  thanks for moving my thread to General.
                  Last edited by Ganesh Ujwal; 12-08-2014, 09:17 PM.

                  Comment

                  • Brian Bushnell
                    Super Moderator
                    • Jan 2014
                    • 2709

                    #10
                    OK, just remember that posting a thread multiple times violates the forum rules, so I deleted it and moved this one over there.

                    Comment

                    • Ganesh Ujwal
                      Member
                      • Dec 2014
                      • 16

                      #11
                      @Brain Bushnell if you know the answer to this question, please post.

                      Comment

                      • Brian Bushnell
                        Super Moderator
                        • Jan 2014
                        • 2709

                        #12
                        I would be happy to, but I'm not a biologist, I'm a programmer; besides, the thread GenoMax found seems to have several good answers in it.

                        Comment

                        • FWOS
                          Epigenomics NGS Beast
                          • Oct 2010
                          • 17

                          #13
                          Hi Ganesh,

                          I think it's as simple as this:

                          RNA loves U

                          Comment

                          • dpryan
                            Devon Ryan
                            • Jul 2011
                            • 3478

                            #14
                            No, it's not that RNA loves U, since RNA had U before there was DNA. Rather, it's that there are benefits to DNA using T (as outlined in Genomax's link).

                            Comment

                            • Ganesh Ujwal
                              Member
                              • Dec 2014
                              • 16

                              #15
                              Originally posted by FWOS View Post
                              Hi Ganesh,

                              I think it's as simple as this:

                              RNA loves U

                              Mod, this type of replies are right or wrong?

                              Comment

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