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A place for discussion of older forums and sequencing technologies.

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Topics: 37 Posts: 67
Last Post: Sequencing analysis
37 67
annguyen
Open Genomics Engine Project
Open discussion forum for Open Genomics Engine contributors and users
Topics: 8 Posts: 39
8 39
The Pipeline
Sequencing technologies without a commercially released platform (Oxford Nanopore, Halcyon Molecular, etc.)
Topics: 81 Posts: 587
81 587
Yohann75
SOLiD
Sequencing by Oligo Ligation/Detection (Life Technologies)
Topics: 462 Posts: 2,440
462 2,440
454 Pyrosequencing
Pyrosequencing in picotiter plates, custom arrays for enrichment/decomplexing. (Roche)
Topics: 743 Posts: 3,966
Last Post: Rapid Libraries
743 3,966
pmiguel
by pmiguel
Polonator
"Open Source" instrument and sequencing by ligation chemistry (Danaher Motion-Dover)
Topics: 6 Posts: 65
6 65
Guest's Avatar
by Guest
Helicos / Direct Genomics
True Single Molecule Sequencing, originally by Helicos, tech acquired by Direct Genomics
Topics: 24 Posts: 114
24 114
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  • seqadmin
    Addressing Off-Target Effects in CRISPR Technologies
    by seqadmin






    The first FDA-approved CRISPR-based therapy marked the transition of therapeutic gene editing from a dream to reality1. CRISPR technologies have streamlined gene editing, and CRISPR screens have become an important approach for identifying genes involved in disease processes2. This technique introduces targeted mutations across numerous genes, enabling large-scale identification of gene functions, interactions, and pathways3. Identifying the full range...
    08-27-2024, 04:44 AM
  • seqadmin
    Selecting and Optimizing mRNA Library Preparations
    by seqadmin



    Sequencing mRNA provides a snapshot of cellular activity, allowing researchers to study the dynamics of cellular processes, compare gene expression across different tissue types, and gain insights into the mechanisms of complex diseases. “mRNA’s central role in the dogma of molecular biology makes it a logical and relevant focus for transcriptomic studies,” stated Sebastian Aguilar Pierlé, Ph.D., Application Development Lead at Inorevia. “One of the major hurdles for...
    08-07-2024, 12:11 PM

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