Solexa sequencing/mRNA sequencing

[Riazm]

hi everyone,
I wonder if someone explains the difference in solexa sequencing and mRNA sequencing. thanks

[pmiguel]

"Solexa" is the name of a company purchased by Illumina some years ago. Sometimes still used to refer to sequencers now sold by Illumina, the term is losing currency as it does not seemed to be used by Illumina. Illumina sequencers are the most popular "next generation" sequencers, having come to dominate the nascent next gen market prior to their acquisition by Illumina.

"mRNA sequencing" would be a generic term for producing the sequence of at least part of a messenger RNA. There are many methodologies that allow mRNA (and, more commonly pools of mRNAs) to be sequenced on Illumina and many other sorts of sequencers.

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Phillip

[Riazm]

thanks very much sir, It means both technologies are same but the name are different. mRNA sequencing could be named solexa sequencing?
thanks and regards

[pmiguel]

No, not at all.

Many types of sequencing can be undertaken on an Illumina (Solexa) sequencer. This includes "mRNA sequencing", but is not limited to it.

Further, "mRNA sequencing" can be undertaken on many instruments.

So it is not correct to refer to "mRNA sequencing" as "solexa sequencing" or vice versa.

Repeating in Google-translated French:
Répétition dans Google-traduits française:

Non, pas tout.

De nombreux types de séquençage peuvent être entrepris sur une Illumina (Solexa) séquenceur. Ceci inclut "séquençage ARNm", mais n'est pas limité à qu'elle.

En outre, «séquençage ARNm» peut être entrepris sur de nombreux instruments.

Donc c'est pas correct pour désigner «ARNm séquençage» comme «Solexa séquençage» ou vice versa.

--
Phillip

[Riazm]

Ok i got it, thanks again

[dongzw]

Thank you, pmiguel, for your very nice answer and patience