What are considered "good" ranges for intensity and % alignment?
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GERALD summary information
I am referring to the GERALD summary information and what are considered to be "good" ranges. Is there any documentation on this? I am not running the sample, just receiving the fastq files. -
Thanks
Thanks for all your help.
Some friends at WashU answered my questions.Comment
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I am working with at lab that will be doing pharmacogenetic assays using MiSeq. Getting the genotypes will be straightforward but copy number detection for CYP2D6 is a challenge on any platform because of confusion with CYP2D7. Does anyone know if there is a recommended way of estimating copy numbers with MiSeq?
Thanks,
Don Rule
Translational SoftwareComment
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NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification, detection...Yesterday, 06:46 AM -
Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM
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