FastQC low mean quality score for first 35 bp - dumpster fire or still salvagable?

[Kai_Buechner]

Dear all,

I conducted an experiment with (unfortunately) outdated chemicals. Some quality score look acceptable, but the first 35 bp of some of my samples do not really look that good.

My question: is there some way to still work with this data?

The parameters:
NextSeq 550 High Output kit with 75 bp paired end reads
Illumina stranded mRNA library prep kit

Thank you for your help!
Kai