I have a sequenced paired end data of S.cerevisisae, sequenced by Illumina, I was wondering why there is low coverage in the centromeric regions compared to the rest of the genome. There are centromeric regions that even do not have any coverage. My average coverage is 30, and the reads are 100bp long. The fragments that was sequenced had a length of 600bp (reads are 100bp form one end and 100bp from other , paired reads)
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM -
Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.
We asked six companies the same four questions to learn about their latest products. The new technologies bring a lot to the table, including rethinking sequencing...
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