I read the paper Reducing assembly complexity of microbial genomes with single-molecule sequencing, and I find it use PacbioToCA to do self-correction. But I think PacbioToCA uses short reads(NGS reads) to do hybrid read correction, not self. And the paper says it uses PBcR and NGS reads to do hybrid read correction, and in the section PBcR correction pipeline in that paper, it mentioned it's feasible to use C2 reads to do self correction. I'm confused what method it really use to do self correction.
Unconfigured Ad
Collapse
X
-
http://canu.readthedocs.io/en/stable/ Is the latest implementation of a pipeline to assemble Pacbio only data based on Celera Assembler (CA).
Latest Articles
Collapse
-
by SEQadmin2
Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...-
Channel: Articles
Yesterday, 09:55 AM -
-
by SEQadmin2
Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.
We asked six companies the same four questions to learn about their latest products. The new technologies bring a lot to the table, including rethinking sequencing...-
Channel: Articles
-
ad_right_rmr
Collapse
News
Collapse
| Topics | Statistics | Last Post | ||
|---|---|---|---|---|
|
Started by SEQadmin2, Yesterday, 05:39 AM
|
0 responses
13 views
0 reactions
|
Last Post
by SEQadmin2
Yesterday, 05:39 AM
|
||
|
Started by SEQadmin2, 10-13-2026, 09:56 AM
|
0 responses
15 views
0 reactions
|
Last Post
by SEQadmin2
10-13-2026, 09:56 AM
|
||
|
Started by SEQadmin2, 10-09-2026, 11:14 AM
|
0 responses
27 views
0 reactions
|
Last Post
by SEQadmin2
10-09-2026, 11:14 AM
|
||
|
Started by SEQadmin2, 09-29-2026, 09:51 AM
|
0 responses
78 views
0 reactions
|
Last Post
by SEQadmin2
09-29-2026, 09:51 AM
|
Comment