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  • SureSelect exome sequencing on SOLiD

    Have many people tried SureSelect Whole exome capture and sequencing on the SOLiD yet? I don't see many publications out there and hear conflicting reports of the data quality and % of zero coverage. We are deciding whether to just do exomes on the HiSeq and use the SOLiD for transcriptomes.

  • #2
    We did it over a year ago and it worked well.

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    • #3
      Do it routinely. The data quality is more in the library prep than the machine. Though we do get some nice SNP calls with less than 10x coverage.

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