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  • Improving the Sensitivity of Gene Fusion Detection from Archer® FusionPlex® Panels

    Recent studies point to promising new therapeutic options that can be applied in the presence of certain gene fusion events (such as NTRK gene fusions). Diagnostic labs can use RNA sequencing to detect such fusion events. The source material (e.g. tumor tissue) has to be prepared for sequencing using custom-made assays or using commercial assays such as Archer® FusionPlex®.


    Given that recently a new module for detecting fusion events was introduced to the Seamless NGS software platform, the developers were interested in how sensitive their approach is on existing data. Find out how the software platform performed: https://www.ecseq.com/blog/2020/Impr...ionPlex-Panels

    ecSeq Bioinformatics is Europe’s leading provider of hands-on bioinformatics workshops and professional data analysis in the field of Next-Generation Sequencing (NGS).

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  • seqadmin
    Strategies for Sequencing Challenging Samples
    by seqadmin


    Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...
    03-22-2024, 06:39 AM
  • seqadmin
    Techniques and Challenges in Conservation Genomics
    by seqadmin



    The field of conservation genomics centers on applying genomics technologies in support of conservation efforts and the preservation of biodiversity. This article features interviews with two researchers who showcase their innovative work and highlight the current state and future of conservation genomics.

    Avian Conservation
    Matthew DeSaix, a recent doctoral graduate from Kristen Ruegg’s lab at The University of Colorado, shared that most of his research...
    03-08-2024, 10:41 AM

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