Clinical Sequencing

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Using Copy Number Alterations detected in other studies for the same tumor cell line by petch Started by petch, 11-13-2022, 09:42 AM	0 responses 39 views 1 like	Last Post by petch 11-13-2022, 09:42 AM
Error with per tile sequence quality (by FastQC) by npawarut Started by npawarut, 04-05-2022, 06:56 PM	0 responses 1,295 views 0 likes	Last Post by npawarut 04-05-2022, 06:56 PM
The Next Generation Sequencing Advances Liquid Biopsy Companion Diagnostics by vivianshaw Started by vivianshaw, 12-07-2021, 08:02 PM	0 responses 14 views 0 likes	Last Post by vivianshaw 12-07-2021, 08:02 PM
Up-to-date expert knowledge is the key to generating impactful biological insights by ecSeq Bioinformatics Started by ecSeq Bioinformatics, 07-31-2015, 05:58 AM	1 response 21,061 views 0 likes	Last Post by zainsas 02-22-2021, 04:01 AM
Improving the Sensitivity of Gene Fusion Detection from Archer® FusionPlex® Panels by ecSeq Bioinformatics Started by ecSeq Bioinformatics, 03-10-2020, 08:03 AM	0 responses 1 view 0 likes	Last Post by ecSeq Bioinformatics 03-10-2020, 08:03 AM
Transferring patient's genetic testing data to the cloud: 5 myths by ecSeq Bioinformatics Started by ecSeq Bioinformatics, 02-29-2020, 01:41 AM	1 response 7,596 views 0 likes	Last Post by LarsB 03-03-2020, 10:47 PM
Automate your Twist Human Core Exome Kit Data Analysis by ecSeq Bioinformatics Started by ecSeq Bioinformatics, 01-21-2020, 08:32 AM	0 responses 4,874 views 0 likes	Last Post by ecSeq Bioinformatics 01-21-2020, 08:32 AM
Mean Read length for RNA sequenced on Oncomine comprehensive panel by mehrom01 Started by mehrom01, 02-25-2019, 12:09 PM	0 responses 11,522 views 0 likes	Last Post by mehrom01 02-25-2019, 12:09 PM
Who is doing clinical sequencing here? by nilshomer Started by nilshomer, 08-27-2012, 02:46 PM	30 responses 32,163 views 0 likes	Last Post by jdmendez 07-23-2018, 06:30 AM
Allele frequency discrepancies in Illumina data? by puggie Started by puggie, 06-20-2018, 05:25 AM	0 responses 6,871 views 0 likes	Last Post by puggie 06-20-2018, 05:25 AM

Topics	Statistics	Last Post
Discovery of Histone-Organized Chromatin in Bacteria by seqadmin Started by seqadmin, Today, 06:36 PM	0 responses 6 views 0 likes	Last Post by seqadmin Today, 06:36 PM
ESPRESSO: Quantifying transcript isoforms from long-read sequencing by seqadmin Started by seqadmin, 01-23-2023, 12:48 PM	0 responses 29 views 0 likes	Last Post by seqadmin 01-23-2023, 12:48 PM
Top 11 Takeaways from JP Morgan Healthcare 2023 by seqadmin Started by seqadmin, 01-18-2023, 04:23 PM	1 response 116 views 0 likes	Last Post by OlgaCaswell 01-25-2023, 05:27 AM

A Brief Overview and Common Challenges in Single-cell Sequencing Analysis

by seqadmin

The introduction of single-cell sequencing has advanced the ability to study cell-to-cell heterogeneity. Its use has improved our understanding of somatic mutations¹, cell lineages², cellular diversity and regulation³, and development in multicellular organisms⁴. Single-cell sequencing encompasses hundreds of techniques with different approaches to studying the genomes, transcriptomes, epigenomes, and other omics of individual cells. The analysis of single-cell sequencing data i...
- Channel: Articles
01-24-2023, 01:19 PM
Introduction to Single-Cell Sequencing

by seqadmin

Single-cell sequencing is a technique used to investigate the genome, transcriptome, epigenome, and other omics of individual cells using high-throughput sequencing. This technology has provided many scientific breakthroughs and continues to be applied across many fields, including microbiology, oncology, immunology, neurobiology, precision medicine, and stem cell research.

The advancement of single-cell sequencing began in 2009 when Tang et al. investigated the single-cell transcriptomes...
- Channel: Articles
01-09-2023, 03:10 PM

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