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Any non-primary sequence heritable modification of genetic material. ChIP-SEQ, DNA methylation (Bisulfite-SEQ), chromatin modifications (methylation, acetylation, etc), non coding RNA.
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Started by ECO, 11-03-2008, 12:50 AM
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20 responses
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by sameet
04-26-2010, 04:40 PM
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Started by yxl, 02-24-2011, 10:09 AM
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by yxl
02-24-2011, 10:09 AM
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Started by jdub, 12-23-2010, 06:31 PM
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5 responses
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by NGene
02-11-2011, 05:58 AM
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Started by Geneus, 12-10-2010, 08:54 PM
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1 response
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by zymo
12-14-2010, 10:13 AM
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Started by ronindan, 12-06-2010, 03:49 AM
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6 responses
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by ETHANol
12-07-2010, 02:00 AM
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Started by jdub, 12-01-2010, 09:18 PM
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1 response
4,222 views
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by jdub
12-01-2010, 09:20 PM
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Started by sonja, 11-17-2010, 02:16 AM
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3 responses
3,061 views
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by ETHANol
11-22-2010, 01:53 AM
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Started by Autotroph, 11-22-2010, 01:51 AM
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2,075 views
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by Autotroph
11-22-2010, 01:51 AM
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Started by zeam, 11-18-2010, 09:17 PM
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1 response
4,715 views
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by fkrueger
11-19-2010, 01:12 AM
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Started by burza, 10-29-2010, 11:31 AM
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10 responses
4,272 views
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by GKM
11-09-2010, 05:38 PM
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ChIP and SDS
by jdub
Started by jdub, 11-04-2010, 11:51 AM
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3 responses
5,044 views
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by Hamid
11-04-2010, 01:30 PM
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by SEQadmin2
Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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Yesterday, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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Channel: Articles
07-01-2026, 11:43 AM -
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by SEQadmin2
I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.
Here are nine questions we think about, in roughly the order they matter, before...-
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Started by SEQadmin2, Yesterday, 10:08 AM
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by SEQadmin2
Yesterday, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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by SEQadmin2
07-07-2026, 11:05 AM
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Started by SEQadmin2, 07-02-2026, 11:08 AM
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by SEQadmin2
07-02-2026, 11:08 AM
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