*Posted also under Bioinformatics
Hi all,
I am trying to map two mature miRNA sequences to the human genome. My background is not bioinformatics or comp-sci but, having searched the web, I am under the impression I need to use Novoalign or Bowtie.
The problem is that when I get to these websites and read about how to use these programs, my eyes gloss over and I am like
Reading the help guides has not added any clarity.
Can anyone help a non-computer person understand how to use Novoalign? I am using a MacOSx. I am not sure if I need adapter stripping - all I know is that the miRNA I want to map are "mature" sequences from the literature.
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The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
This convergence of genetics, immunology, and computation...09-01-2026, 05:41 AM