Are these excluded from Tophat if they are from diffferent chromosomes?
Any suggestions on packages that can do this determination?
Any suggestions on packages that can do this determination?
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I donot think so....but there are some packages for DNA fusion/translocation detection.. -
townway, could you point to dna fusion packages? I know pemer is a good one for translocation detection, but probably not for rna-seq data--
bioinfosmComment
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right now there are some for DNA, like pemer, breakdancer. and I have not seen one for rna-seq. if you know, please post me as wellComment
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I think for tophat, it does not report fusion transcript from different chromosomeComment
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Including TopHat there are many more tools which can detect fusions both within and between chromosomes.Comment
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The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
This convergence of genetics, immunology, and computation...09-01-2026, 05:41 AM
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