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  • RockChalkJayhawk
    Senior Member
    • Mar 2009
    • 192

    #1

    Detecting fusion transcripts in PE_RNA-Seq

    Are these excluded from Tophat if they are from diffferent chromosomes?

    Any suggestions on packages that can do this determination?
  • townway
    Member
    • May 2009
    • 41

    #2
    I donot think so....but there are some packages for DNA fusion/translocation detection..

    Comment

    • bioinfosm
      Senior Member
      • Jan 2008
      • 483

      #3
      townway, could you point to dna fusion packages? I know pemer is a good one for translocation detection, but probably not for rna-seq data
      --
      bioinfosm

      Comment

      • townway
        Member
        • May 2009
        • 41

        #4
        right now there are some for DNA, like pemer, breakdancer. and I have not seen one for rna-seq. if you know, please post me as well

        Comment

        • lmf_bill
          Member
          • Jul 2008
          • 36

          #5
          I think for tophat, it does not report fusion transcript from different chromosome

          Comment

          • bharati
            Member
            • Mar 2012
            • 38

            #6
            Including TopHat there are many more tools which can detect fusions both within and between chromosomes.

            Comment

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