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We currently have a GAIIx but are upgrading to the HiSeq. Today I noticed that the HiSeq library prep kit is over $500 more than the old paired end library kit. Does anyone know what the difference is? Will my old libraries work on the new cBot?
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I'm not sure, cause I didn't have much experience in library construction, but there's no big changes between GA2 and Hiseq, just add one flowcell access and more efficient in flowcell itself, so I suppose the old one could be work, not so sure~~ -
They told me the library kits work the same. The cBot cluster kit is different from the old cluster station though (and more expensive, how surprising).Comment
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Data variability is still an issue in sequencing technologies despite the advances in reproducibility and accuracy of these platforms. But the problem does not originate in the sequencing itself, but in the previous steps, before the sample reaches the sequencer.
The first step is collection, followed by preservation and sample preparation for analysis. Most scientists overlook those steps, but not being careful might just be skewing the experiment’s results.
...06-02-2026, 10:05 AM -
With the launch of new single-cell sequencing platforms in 2026, the field stands at an exciting inflection point. This article surveys the most impactful advances in the field and discusses how they’re reshaping research in cancer, immunology, and beyond.
Introduction
Single-cell sequencing technologies have undergone remarkable advances over the past decade, transitioning from low-throughput experimental approaches to highly scalable platforms capable of...05-22-2026, 06:42 AM
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