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Hi,
Can someone help me understanding what are single and pair end sequencing?
Thanks
Can someone help me understanding what are single and pair end sequencing?
Thanks
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This may be the single most often asked question on this forum. For your homework, you might want to do a search just to see how many times this question has appeared over the years. This will help you get your answer, understand it, and also help with your skills in finding the answer to other questions you may have. This will be quite handy in being able to use the many forum resources available to you here. -
Okay, I will try to find those threads and yes you are right, it will be helpful for me to find other related Q/A.
Thanks!
RabailComment
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Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
...07-09-2026, 11:10 AM -
Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...07-08-2026, 05:17 AM -
Love this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.07-01-2026, 11:43 AM
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