Best magnet plate for beads separation

[hewenjuan]

Hello all,

I am recently doing sequencing library prep in a 96-well plate. I found that especially with small volume, magnet beads separation can take very long. In addition, when I try to remove all the residual solution, I often get beads carryover. I wonder whether getting a better and stronger magnet plate will help. Any suggestions?
The magnet plate I am using:

https://www.thermofisher.com/order/catalog/product/AM10027

Thanks!

[huguesparri]

Hello,
Did you try the Agencourt SPRIPlate 96 (ref. A29164 in the beckman Coulter catalog)?
We use it in our lab and we are rather satisfied with it.
regards,

Hugues

[thermophile]

https://www.alpaqua.com/Products/Magnet-Plates/Magnum-FLX

by far the best plate mag I've tried. it's expensive but if you are doing lots of cleanups and want speed and small volumes it's probably worth it.