Hi,
Recently, Our lab want to buy sonicator.So we evaluate the bioruptor and Misonix.But bioruptor is more expensive and Misonix apply in NGS is less
So we want to ask :
Have someone use the Misonix 4000 for fragement genomic DNA (Solexa system)
Is this symstem good for DNA fragement in 300-100 bp
and May i ask the program.
thanks!
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The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
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