I've been looking into the Illumina TST170 sample prep kit. Reading the protocol, you either make a sheared DNA library or a cDNA library from RNA, then both go into the hybridisation capture based. But the data sheet says that fusions and splice variants can only be detected from RNA for a subset of the 170 genes. Why is this, if they are all going into the same capture?
-
Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM