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Techniques and protocol discussions on sample preparation, library generation, methods and ideas
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Started by JakobHedegaard, 12-13-2011, 07:57 AM
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1 response
3,523 views
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by Olaf Blue
12-13-2011, 08:48 AM
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Started by Sarah_Tulin, 12-12-2011, 01:00 PM
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2,400 views
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by Sarah_Tulin
12-12-2011, 01:00 PM
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Started by BTS, 02-10-2011, 09:07 AM
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8 responses
5,358 views
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by genomehacker
12-08-2011, 11:43 AM
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Started by egunth, 12-01-2011, 10:14 AM
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2 responses
4,394 views
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by egunth
12-01-2011, 12:53 PM
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Started by Mindbomb, 11-30-2011, 07:47 AM
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1 response
2,927 views
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by mudshark
12-01-2011, 12:00 AM
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Started by rrdavis, 11-22-2011, 11:24 AM
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1 response
3,179 views
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by pmiguel
11-23-2011, 07:05 AM
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Started by captainentropy, 08-30-2011, 11:25 PM
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6 responses
12,844 views
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by gringer
11-22-2011, 10:30 AM
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Started by debbiehughes, 11-21-2011, 07:06 AM
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0 responses
2,572 views
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by debbiehughes
11-21-2011, 07:06 AM
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Started by flashnglow, 11-21-2011, 01:44 AM
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1 response
2,436 views
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by niceday
11-21-2011, 05:20 AM
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Started by skblazer, 11-18-2011, 10:14 AM
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3 responses
2,245 views
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Last Post
by pmiguel
11-18-2011, 12:29 PM
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Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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