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I have tried zorro on a genome of 450 MBp and I advise you not to try this. It is far too slow and basically unusable on a genome of this size.
I work on a project together with the developers of GAM and although nothing is public yet (and I am not sure when it will be) I have been testing an updated version designed to handle NGS assemblies and the results are excellent and the speed is also great. I will talk to the developer to ask when a public release could be possible.
Zorro maximum size
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NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification,...10-30-2026, 06:46 AM
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