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  • RFo
    Junior Member
    • May 2012
    • 5

    #1

    Structural variation using paired-end reads

    I have resequenced a bacterial genome using paired-end SOLiD reads (75+35 bp).

    Which software is recommended to detect large insertions / deletions (and may be other structural variations) which makes use of the paired-end data?

    I tried using LifeScope's LargeIndel detection tool, but apparently it's not very useful for prokaryotic genomes.

    Along the same lines: which software would you use if you had Illumina data? Does Illumina have a standard software package to solve such a task?

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