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  • cal123
    started a topic GlimmerHMM

    GlimmerHMM

    Kind of a beginner question here which is not specific to any particular organism. To train GlimmerHMM you need a file with the genes, and a file with the coordinates of the exons within those genes. The genes are downloadable from NCBI, but I am wondering how you get the exon coordinates. Are they also downloadable from NCBI? I feel like they should be, otherwise they wouldn't have the genes available if they didn't have some idea of the intron-exon boundaries within the genes. Or is the availability of the exon information dependent on the degree of annotation of the organism?

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  • seqadmin
    Multiomics Techniques Advancing Disease Research
    by seqadmin


    New and advanced multiomics tools and technologies have opened new avenues of research and markedly enhanced various disciplines such as disease research and precision medicine1. The practice of merging diverse data from various ‘omes increasingly provides a more holistic understanding of biological systems. As Maddison Masaeli, Co-Founder and CEO at Deepcell, aptly noted, “You can't explain biology in its complex form with one modality.”

    A major leap in the field has
    ...
    02-08-2024, 06:33 AM

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