Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • ComputGuy
    Junior Member
    • Sep 2013
    • 1

    #1

    Enrichment analysis with DAVID tool - question

    Hi All,

    I am still new in the field and I have a question please.

    I have a dataset of gene expressions and I am running biclustering methods over them. The dataset is colon cancer dataset, When I get the new biclusters I want to do biological validation; enrichment analysis to find how many genes are enriched in each bicluster. I want to use DAVID tool for that.
    My question is when I upload my gene set to DAVID tool, I choose "Functional Annotation Clustering" then I have set of clusters for the set of genes that I uploaded with different gene enrichment score. How can I find "Proportion of biclusters significantly enriched" as it has been done in Figure 3 of this paper "A systematic comparison and evaluation of biclustering methods
    for gene expression data"
    http://bioinformatics.oxfordjournals....full.pdf+html

    Any help please? Any hint really appreciated.

    Could anyone with experience direct me please.
    Thanks!
    Last edited by ComputGuy; 09-23-2013, 11:23 AM.

Latest Articles

Collapse

  • SEQadmin2
    16S/ITS Profiling vs. Shotgun Metagenomics: What Changes in Your Workflow?
    by SEQadmin2




    NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification, detection...
    Yesterday, 06:46 AM
  • SEQadmin2
    Multiomic Liquid Biopsy: What DNA/RNA Panels Reveal That DNA Alone Can’t
    by SEQadmin2



    Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?

    Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating
    ...
    10-14-2026, 09:55 AM

ad_right_rmr

Collapse

News

Collapse

Topics Statistics Last Post
Started by SEQadmin2, 10-28-2026, 09:57 AM
0 responses
29 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 10-28-2026, 09:51 AM
0 responses
20 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 10-22-2026, 11:13 AM
0 responses
71 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 10-22-2026, 10:48 AM
0 responses
48 views
0 reactions
Last Post SEQadmin2  
Working...