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Hi,
Does anybody know some tool to correct genome annotations?
Thanks in advance!
Does anybody know some tool to correct genome annotations?
Thanks in advance!
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Last edited by diego diaz; 04-14-2015, 08:53 AM. -
It depends on what you want to do, are you preparing a genome submission yourself, or want to submit changes to an NCBI annotated genome? Or just clean up your own copy for internal use?Scott Monsma
Sr Scientist at Lucigen -
We want to clean up the annotation. Some genes are shown as more than one due to frameshifts generating stop codons. Frameshift seem to occur because homopolimersComment
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Are the frameshifts just due to sequence errors? Or actually occur biologically?
NCBI's submission tools might be able to help you find the annotations that have the problem, but they're a bit of a pain to work with. You would need to convert your annotations list to their 5 column table format, and then use tbl2asn to validate the features listed in the table.Scott Monsma
Sr Scientist at LucigenComment
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