Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • binfoUser
    Member
    • Jan 2016
    • 22

    #1

    Java library to manipulate VCF files

    I'm starting to work with VCF files and other types of files with genes annotation.
    I want to know if there is any Java libraries that I can use to manipulate vcf files.

    Thank you!
  • lindenb
    Senior Member
    • Apr 2010
    • 143

    #2
    https://github.com/samtools/htsjdk



    example:

    Code:
    import htsjdk.variant.vcf.*;
    import htsjdk.variant.variantcontext.*;
    import htsjdk.tribble.readers.*;
    public class MinVcf
    	{
    	public static void main(String args[]) throws Exception
    		{
    		VCFCodec codec= new VCFCodec();
    		LineReader r= LineReaderUtil.fromBufferedStream(System.in);
    		LineIteratorImpl t= new LineIteratorImpl(r);
    		codec.readActualHeader(t);
    		while(t.hasNext())
    			{
    			VariantContext ctx = codec.decode(t.next());
    			}
    		r.close();
    		}
    	}

    Comment

    • binfoUser
      Member
      • Jan 2016
      • 22

      #3
      I saw that library but I have to use Ant to build the jarfile. I installed Ant and when I run the code to buil the jar I get an error:

      Code:
      BUILD FAILED
      /home/usr/Documents/htsjdk-master/build.xml:96: The following error occurred while executing this line:
      /home/usr/Documents/htsjdk-master/build.xml:241: Compile failed; see the compiler error output for details.
      I tried but I always have this error.

      Comment

      • lindenb
        Senior Member
        • Apr 2010
        • 143

        #4
        as it is said: "see the compiler error output for details.".
        So, what's the compiler output ?

        Comment

        • binfoUser
          Member
          • Jan 2016
          • 22

          #5
          I think is this:

          [javac] /home/usr/Documents/htsjdk-master/build.xml:241: warning: 'includeantruntime' was not set, defaulting to build.sysclasspath=last; set to false for repeatable builds
          [javac] Compiling 410 source files to /home/usr/Documents/htsjdk-master/classes
          [javac] javac: invalid target release: 1.8
          [javac] Usage: javac <options> <source files>
          [javac] use -help for a list of possible options

          Comment

          • lindenb
            Senior Member
            • Apr 2010
            • 143

            #6
            you need to install java 1.8 :

            https://github.com/samtools/htsjdk " Java 8 is now required."

            and set JAVA_HOME if needed.

            Comment

            • binfoUser
              Member
              • Jan 2016
              • 22

              #7
              It worked! But I was reading this page building htsjdk and it was talking about 1.6. I was confused because of that.

              Thank you!

              Comment

              Latest Articles

              Collapse

              • SEQadmin2
                Beyond CRISPR/Cas9: Understand, Choose, and Use the Right Genome Editing Tool
                by SEQadmin2



                CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).

                Despite this, “CRISPR helped turn genome editing from a specialized technique into
                ...
                07-31-2026, 11:01 AM
              • SEQadmin2
                Proteomic Platforms: How to Choose the Right Analytical Strategy to Improve Detection and Clinical Applications
                by SEQadmin2


                Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.

                The systematic characterization of the human proteome has
                ...
                07-20-2026, 11:48 AM

              ad_right_rmr

              Collapse

              News

              Collapse

              Topics Statistics Last Post
              Started by SEQadmin2, Yesterday, 10:35 AM
              0 responses
              7 views
              0 reactions
              Last Post SEQadmin2  
              Started by SEQadmin2, 08-06-2026, 07:41 AM
              0 responses
              25 views
              0 reactions
              Last Post SEQadmin2  
              Started by SEQadmin2, 08-03-2026, 10:13 AM
              0 responses
              45 views
              0 reactions
              Last Post SEQadmin2  
              Started by SEQadmin2, 07-31-2026, 02:55 AM
              0 responses
              48 views
              0 reactions
              Last Post SEQadmin2  
              Working...